REDUCTION OF URATE DEPOSITION
ONGOING URATE DEPOSITION
- 0-4.0 mg/dL5,6
- 4.1-5.9 mg/dL5,7
- 6.0-6.8 mg/dL5,8,9
- >6.8 mg/dL2,10,11
0-4.0 mg/dL5,6
Potential to
- Resolve tophi faster
- Expedite the reduction of urate burden
- 0-4.0 mg/dL5,6
- 4.1-5.9 mg/dL5,7
- 6.0-6.8 mg/dL5,8,9
- >6.8 mg/dL2,10,11
4.1-5.9 mg/dL5,7
Potential to
- Slow dissolution of tophi (visible and nonvisible)5,7
- Decrease flare frequency5,7
- 0-4.0 mg/dL5,6
- 4.1-5.9 mg/dL5,7
- 6.0-6.8 mg/dL5,8,9
- >6.8 mg/dL2,10,11
6.0-6.8 mg/dL5,8,9
Potential to
- Slow gout progression
- Maintain urate burden, and flares can continue
- 0-4.0 mg/dL5,6
- 4.1-5.9 mg/dL5,7
- 6.0-6.8 mg/dL5,8,9
- >6.8 mg/dL2,10,11
>6.8 mg/dL2,10,11
Potential to
- Continue to deposit urate in the joints and tissues, including in the organs
- Increase flare frequency