REDUCTION OF URIC ACID DEPOSITION
ONGOING URATE DEPOSITION
- 0-4.0 mg/dL1,2
- 4.1-5.9 mg/dL1,8
- 6.0-6.8 mg/dL1,3,4
- >6.8 mg/dL5,7
0-4.0 mg/dL1,2
Potential to
- Resolve tophi faster
- Expedite the reduction of
uric acid burden
- 0-4.0 mg/dL1,2
- 4.1-5.9 mg/dL1,8
- 6.0-6.8 mg/dL1,3,4
- >6.8 mg/dL5,7
4.1-5.9 mg/dL1,8
Potential to
- Slow dissolution of tophi (visible and nonvisible)1,9
- Decrease flare frequency1,9
- 0-4.0 mg/dL1,2
- 4.1-5.9 mg/dL1,8
- 6.0-6.8 mg/dL1,3,4
- >6.8 mg/dL5,7
6.0-6.8 mg/dL1,3,4
Potential to
- Slow gout progression
- Urate burden unchanged, and flares can continue
- 0-4.0 mg/dL1,2
- 4.1-5.9 mg/dL1,8
- 6.0-6.8 mg/dL1,3,4
- >6.8 mg/dL5,7
>6.8 mg/dL5,7
- Urate continues to deposit in the joints and tissues, including organs
- Flares can increase in frequency